Scientist – Medicinal Chemistry

iTeos Therapeutics is a publicly-held (NASDAQ: ITOS), clinical-stage biopharmaceutical company dedicated to extending and improving the lives of cancer patients by designing and developing next generation immunotherapies.

Based in Gosselies, Belgium and Cambridge, MA, iTeos Therapeutics was founded out of the Ludwig Institute for Cancer Research (LICR) and the de Duve Institute (UCLouvain) in 2011.

In March 2020, the Company completed a $125 million Series B2 financing, and in July 2020, we completed our IPO raising over $230million of gross proceeds. In June 2021, iTeos entered into a transformative $2.145 billion co-development and co-commercialization agreement with GSK for EOS-448, iTeos’s anti-TIGITmonoclonal antibody. As a well-capitalized biotech company iTeos is positioned to continue to develop our clinical pipeline and maintain our investments in our discovery research team to leverage our fantastic science to improve the lives of cancer patients.

For more information, please visit www.iteostherapeutics.com.

iTeos Therapeutics is now a world-class biotech in cancer immunotherapy. To carry on its growth, expand its pipeline and reinforce its team, iTeos Therapeutics is looking for a Scientist – Medicinal Chemistry.

Responsibilities

iTeos Therapeutics is looking for a highly motivated and skilled Scientist to join the Medicinal Chemistry team in the Research and Development Department. The successful candidate will be responsible for the synthesis and design of small molecules, and manage the daily laboratory operations.

Your main responsibilities are:

• Design and execute organic synthesis of small molecule compounds.
• Optimize synthetic routes and develop new methodologies to streamline processes.
• Conduct structure-activity relationship studies to support projects from hit to lead to lead optimization phases.
• Stay informed of the state of the art of organic chemistry methodologies and techniques and propose their application to ongoing projects.
• Manage and maintain laboratory operations, including ordering and maintaining supplies, equipment maintenance, and ensuring a safe and compliant working environment.
• Train and mentor junior Scientists and Research Assistants on laboratory techniques and procedures.

Profile

• PhD in Organic Chemistry or related field with a strong background in synthetic chemistry, with 4 years of experience.
• Excellent laboratory skills, with hands-on experience in synthetic organic chemistry techniques and instrumentation.
• Strong problem-solving and analytical skills.
• Experience in lab management, including inventory management, equipment maintenance, and safety protocols.
• Excellent communication and interpersonal skills. Excellent command of English.
• Ability to work effectively in a fast-paced and dynamic environment.
• Passion for bench work and a desire to advance drug discovery.

Offer

• A stimulating position within a high-potential innovative biotech company.
• The opportunity to work in a science-driven, dynamic, respectful, and professional environment.
• A challenging scientific and business growth in which you get to bring your knowledge and skills.
• A permanent contract with an attractive salary package in line with the position responsibilities and your experience.

Your application and related information you would share will remain strictly confidential.