Neuvasq Biotechnologies is a high-potential innovative preclinical-stage biotech company dedicated to extending and improving the lives of patients with CNS disorders, including those suffering from vascular retinopathies. Neuvasq’s science aims at safeguarding or restoring the integrity of the Blood-Brain and Blood-Retinal Barriers.
Based in Gosselies, Belgium, Neuvasq was founded out of the ULB in 2021. The company completed a 20 million€ Series A financing round. The human-sized, smart and passionate team currently focuses on building a strong pre-clinical and clinical pipeline. For more info, please visit www.neuvasq.com.
To help drive the development of its product pipeline, Neuvasq is looking for a Senior Research Associate, Protein Chemistry / Molecular & Cell Biology (M/F).
Responsibilities
As a Senior Research Associate you join the Cell-Biology/Protein Chemistry group within the R&D Department. You are responsible for developing and carrying out biochemical and cell-based assays and daily activities in the lab.
Your main responsibilities are:
- Express and purify engineered proteins for downstream evaluation.
- Support the development of cell-based assays that recapitulate various aspects of the biology of the blood-brain barrier.
- Evaluate drugs for their ability to interfere with pathways involved in the blood-brain barrier homeostasis.
- Contribute to the development of engineered cell lines to support assay development.
- Collaborate with other scientists for the design of in vivo studies aiming at the evaluation of selected molecules in relevant disease models.
- Comply with relevant regulations, guidelines, and Standard Operating Procedures (SOPs).
- Participate in lab management activities.
Profile
- Bachelor’s or Master’s degree in biochemistry, biology, life sciences or related field.
- At least 5 years experience in a comparable position in a biotech/industrial environment.
- Experience in protein purification techniques such as affinity chromatography, IEX, HIC and SEC.
- Experience in vector design and recombinant protein expression in eukaryotic systems.
- Knowledge of protein chemistry techniques, such as SDS-PAGE, western-blot, or ELISA. Experience with FACS or Biacore/Octet would be an additional asset.
- Good knowledge of molecular biology and cloning techniques. Knowledge of CRISPR-Cas9 and/or AAV or lentiviral vectors is a plus.
- Experience in cell culture techniques, including ideally primary cell culture.
- Well organized, flexible, and rigorous. Team-spirit oriented. Ability and willingness to learn.
- Previous experience in CNS biology is a plus.
Offer
- A stimulating position within a high-potential innovative biotech company.
- The opportunity to work in a science-driven, dynamic, respectful, and professional team.
- A challenging scientific and business growth in which you get to bring your skills.
- A permanent contract with an attractive salary package in line with the position responsibilities and your experience.
Your application will remain strictly confidential.